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diagnosis clinical hematology causes algorithm blood path smear rash skin skinrash thrombocytosis deficiency nutrition oncology palpable petechiae platelets purpura secondary
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
each of the above photos ... Dacrocytes are found ... metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Two target cells are ... seen in the left photo ... present in the left photo ... with hemolytic anemias ... Clinical #Path #BloodSmear
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
In the right photo ... seen in hemolytic anemias ... microangiopathic hemolytic anemia ... is mechanical trauma ... Clinical #Path #BloodSmear
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... rheumatologic, trauma ... Thrombocytosis #Differential ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Post-op surgery • Trauma ... Iron deficiency anemia ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... Acute blood loss: Trauma ... Production #Index #hematology ... #anemia #differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... endocarditis • Trauma ... renal failure • Uremia ... Systemic #Secondary #dermatology ... #Differential #
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
by Etiology - Differential ... Physical: • Trauma ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
• Mechanical Trauma ... lactam antibiotics are ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Sickle cells These photos show sickle cells on peripheral blood smears. In the left photo target cells
In the left photo ... target cells are ... no significant anemia ... sickle unless they are ... Clinical #Path #BloodSmear
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