73 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Trauma • ... Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... Diagnosis of TTP: • Rare ... Thrombocytopenic #Purpura ... #rheumatology # ... hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... infarction, Severe trauma ... Diagnosis #Algorithm #hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Non-infectious (malignancy, rheumatologic ... , trauma) • Post-splenectomy ... Thrombocytosis #Differential ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Post-op surgery • Trauma ... effect following treatment ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
challenging and are ... with devastating differential ... palpable, the differential ... #Diagnosis #Dermatology ... #Nonpalpable #Differential
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenic #purpura ... Diagnosis #Table #Hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... vascular integrity (trauma ... #Diagnosis #Dermatology ... Rash #Petechiae #Purpura ... Palpable #Algorithm #Differential
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
thrombocytopenia are ... thrombocytopenic purpura ... #Diagnosis #Hematology ... Thrombocytopenia #Differential