46 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Diuretics (late) • High ... , Gitelman Syndrome ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... → Hypokalemia Metabolic ... #Syndrome #Pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Diuretics (late) • High ... , Gitelman Syndrome ... hyperaldosteronism • High ... Diagnosis #Algorithm #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Low intake • Metabolic ... Renal Losses: • Metabolic ... • HTN, High Aldosterone ... , Gitelman syndrom ... potassium #low #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Syndrome: Distal ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High ... aldosteronism • High ... Al, High R - Secondary ... , Gitelman's syndrome ... Diagnosis #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis
Chloride depletion syndromes
 • Gastrointestinal losses
    -
Causes of Metabolic ... chloridorrhea - High-volume ... - Gitelman ... excess syndromes ... <2 mmol/L) #Metabolic
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... to diarrhea, a high ... acidosis, a high ... urine #Algorithm #nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Urinary Chloride • Cl ... Kidney loss of Cl ... - Loss of Cl ... diuretic use, Bartter syndrome ... , Gitelman syndrome
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Hypomagnesemia • Barrter's/Gitelman's ... High Renin, High ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology