43 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... arthritis - SLE ... #Effusions #causes ... #differential #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... life-threatening • Treatment ... : Chronic disease ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
• Specific for SLE ... Treatment: • ... #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... Usual therapeutic management ... : Chronic disease ... #diagnosis #management
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Gastroenteritis: Treatment ... Severity of the Disease ... Concern for HES: • Hematology ... • Additional diagnostic ... #management #gastroenterology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... normal in mild cases ... #Management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Treatment: • ... #management #treatment
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
and Management ... Treatment: • Global ... and Hepatology ... #Management #gastroenterology ... #treatment