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diagnosis differential causes hepatology management treatment lfts secondary ibd transaminitis acute dermatology pediatrics peds pruritus systemic abdominal aki celiac cirrhosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... Injury (DILI) ... Viral Hepatitis ... Cirrhosis #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • NASH, Chronic ... : > 3 • Chronic ... #injury #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... e.g. ascites), Chronic ... hepatitis fibrosis ... #Algorithm #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic ... - Drug-Induced liver ... injury - Viral ... Wilson disease
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Syndrome, Celiac Disease ... , Infiltrative Disease ... #Injury #Differential ... Causes #Acute #algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... presentation • Chronic ... disease 6-9 mo ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Infections: Hepatitis ... HELLP, Celiac disease ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... 5-10x normal - Chronic ... #Patterns #Liver ... #Injury #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... and Management Algorithm ... • Liver is the ... Chronic Hepatitis ... #Algorithm #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Cirrhosis • Chronic ... Viral Hepatitis ... • Acute Viral Hepatitis ... injury) • Ischemic
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