35 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... RBC #Morphology #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Diseases Nail ... Iron deficiency anemia ... discoloration) • Chronic ... #Secondary #dermatology ... #Differential #
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
hemolytic anemia ... Systolic dysfunction ... multifactorial mechanisms Hematologic ... pulmonary Langerhans cell ... Classification #Diagnosis #Differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Infection - Systemic ... Effusions: - Hematologic ... Osteochondroma Hematologic ... Effusions #causes #differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Cholestatic liver disease ... Creatinine & BUN: • Chronic ... renal failure/uremia ... syndrome Psychiatric Disease ... #generalized #dermatology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Diagnosis and Management ... Summary Clinical Signs ... demineralization) • Renal disease ... plasma clonal cell ... #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Chronic ... kidney disease, ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management