18 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... discoloration) • Chronic ... #Secondary #dermatology ... #Differential #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... : Chronic disease ... #lupus #Systemic ... #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... #Systemic #Lupus ... autoantibodies #signs ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... : Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... ) Differential Diagnosis ... Arthritis, AS Treatment ... Recurrent and chronic ... #signs #symptoms
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... pneumonia • Chronic ... Leukocytosis, anemia ... Lung Abscess Differential ... Abscess #pulmonary #differential
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Eosinophilia, asthma, chronic ... purpura: strong sign ... vasculitis, and SLE ... #diagnosis #rheumatology