16 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... syndrome (Clinical ... Oral aphthae : SLE ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... #CNS #neurology ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... valve lesions Abdominal ... pain (20%) Renal disease ... signs #symptoms #diagnosis ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... treatment #summary #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- GI tract: abdominal ... VASCULITIS: • Behçet ... Supply gut -> abdominal ... vasculitis, and SLE ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis ... #testing #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... affects the skin, neurologic ... gut involvement, abdominal ... vasculitis • Behcet ... #Rheumatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
So high index of ... clinical suspicion ... is required for diagnosis ... conditions: Autoimmune (SLE ... - Infectious Diseases
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... - Sarcoidosis, Behcet ... disease - SLE ... #neurology #differential
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
patients with SLE ... So high index of ... clinical suspicion ... - Infectious Diseases ... #pathophysiology