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hematology management syndrome aflp algorithm aortoenteric apml biliary causes cholangitis cirrhosis classification comparison differentiation disorders fatty fistula heat heatstroke illness
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... abdominal pain, headache ... infiltration) Differential ... Diagnosis: Viral ... Liver #Pregnancy #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... Syndrome #TLS #diagnosis ... #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... CKD, CHF, high rate ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... Diagnosis Framework ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... Decreased pulse rate
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
Clinical Signs/Symptoms ... • Should be on differential ... that precedes a later ... Pathophysiology: ... - CMC IM Residency
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