21 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... = nonspecific (nausea ... ) Differential Diagnosis ... Maternal Support - Critical ... Liver #Pregnancy #hepatology
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... actually seen in all ... TreeInBud #Sign #diagnosis ... #clinical #radiology ... #ChestCT #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... • Jaundice (later ... obstruction • ALP ... #workup #hepatology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... Pathophysiology: ... It's typically a late ... #cullensign #em ... #peritonitis #IM
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Neurologic-Centered ... Features: POEMS, AL ... DADS-M, Sporadic, late-onset
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... • Mitchell et al ... fibrillation at a rate ... #Pathophysiology ... #causes #cardiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical ... • Hypocalcemia/Late ... • HAGMA • Late
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... without other cause ... CKD, CHF, high rate ... #diagnosis #comparison
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... - Causes progressive ... features developing later ... Lateral #Sclerosis #neurology