13 results
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... CNS in the early stages ... • Depressive symptoms ... The clinical syndrome ... dementia #AIDS #Neurology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... tissue => Years later ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... #staging #msk
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... pattern of spread, B symptoms ... very high mitotic rate ... Amy Chung, MD, MSc ... Classification #pathophysiology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... history of cancer, HIV ... Altered mental status ... ) • Systemic symptoms ... #neurology #PHANTOMS
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... hypercoagulable states ... MCTD, Sjogren syndrome ... #diagnosis #neurology ... differential #algorithm
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... the tuberculoma (later ... stage) • Headache ... differential #TB #neurology
Management Algorithm for Status Epilepticus

• Assess airway, breathing, and circulation
• Pulse oximetry
• Electrocardiogram
• Finger stick (give
Management Algorithm ... for Status Epilepticus ... at a maximum rate ... Fosphenytoin 20 PE/kg IM ... #Neurology #pharmacology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Albuminuria, nephrotic syndrome ... ulcerated • MSK ... individuals with HIV ... infected without symptoms ... #Syphilis #stages
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... impairment, Mood disorder ... objective evidence of neurologic ... • Acute: - IV ... diagnosis #management #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Hyperreflexia develops later ... Bilateral signs and/or symptoms ... simplex virus, HIV ... diagnosis #management #neurology