22 results
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Summary Acute AIDP ... Pathophysiology ... Treatment: • Plasmapheresis ... #management #treatment
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
HIV, Hepatitis, Syphilis ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... Willis via UNC IM
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... and nephrotic syndrome ... Late (Tertiary) ... Syphilis - Late ... roots, causing a syndrome
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... million units IM ... single dose • Late ... million units IM ... #CDC #CDC2021 #Treatment
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... the absence of treatment ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... prevention of late ... Treatment: • ... ) 1:1000 IM q5-10mins ... #Management #pathophysiology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... Hospital of Baltimore IM ... #Syndrome #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... CKD, CHF, high rate ... transfusion • Pathophysiology ... : No • Treatment
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
cellars, barns and lake ... Cardiopulmonary Syndrome ... Febrile illness + ARDS ... • Autopsy PCR Treatment ... diagnosis #management #treatment