28 results
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Syphilis - CDC 2021 ... Treatment Guidelines ... million units IM ... single dose • Late ... million units IM
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... and nephrotic syndrome ... Late (Tertiary) ... Syphilis - Late ... roots, causing a syndrome
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... the absence of treatment ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... prevention of late ... Treatment: • ... ) 1:1000 IM q5-10mins ... #Management #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... CKD, CHF, high rate ... transfusion • Pathophysiology ... : No • Treatment
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
cellars, barns and lake ... Cardiopulmonary Syndrome ... Febrile illness + ARDS ... • Autopsy PCR Treatment ... diagnosis #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... proliferation rate ... Low calcium • Treatment
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
(IRIS) - Pathophysiology ... factors: - Low CD4 ... duration or OI treatment ... #Inflammatory #Syndrome ... #AIDS
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... occur when the CD4 ... Antimicrobial treatment ... in HIV: • CNS Syphilis ... differential #diagnosis #AIDS