46 results
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... million units IM ... BID for 2 weeks Late ... million units IM ... BostonChiefs #Syphilis
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... and nephrotic syndrome ... Late (Tertiary) ... Syphilis - Late ... roots, causing a syndrome
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Treatment Guidelines ... million units IM ... single dose • Late ... million units IM ... #CDC #CDC2021 #Treatment
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
Genital Lesions - Differential ... • Secondary Syphilis ... (condyloma lata ... ) • Reiter's syndrome ... ) • Behcet's syndrome
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... the absence of treatment ... Albuminuria, nephrotic syndrome ... infection • Late ... early latent • Late
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
HIV, Hepatitis, Syphilis ... Paraprotein-associated (POEMS syndrome ... Willis via UNC IM ... Peripheral #Neuropathy #differential
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... prevention of late ... Treatment: • ... ) 1:1000 IM q5-10mins ... #Management #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... CKD, CHF, high rate ... transfusion • Pathophysiology ... : No • Treatment
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Short Stature (Late ... • Turner Syndrome ... Panhypopituitarism Treatment ... #ShortStature #Differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1