16 results
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Antiarrhythmics ... • Slows sinus rate ... EricsMedicalLectures/ #Antiarrhythmics ... Classification #Classes ... #cardiology #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... Vaughan #Williams #Pharmacology ... Classification #Classes ... #pathophysiology ... #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... #Pharmacology # ... Classification #Classes ... #pathophysiology
Abnormalities in Rate and Rhythm of Breathing 
Normal 
The respiratory rate is about 14—20 per min
has a number of causes ... Other causes include ... punctuated by frequent sighs ... Occasional sighs ... Causes include
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Uncommon Causes ... crackles in the right ... of other common causes ... - The classic ... pulmonary #edema #causes
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... limits so digoxin ... #cardiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Discoid Rash • UV light ... keratinocytes but abnormal ... Manifestations #pathophysiology ... #diagnosis #signs
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... Pathophysiology: ... bleeding, which might ... pregnancy, or other causes ... It's typically a late
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... • Jaundice (later ... • ALT & AST normal
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... Decreased pulse rate ... - Core temp normal ... differential #diagnosis #causes