19 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... Decreased heart rate ... #Pharmacology # ... Pathophysiology
Atrial Fibrillation Overview

Symptoms:
Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

1. Why?
Cardiac:
• Valvular heart disease
•
Palpitations, light-headedness ... Rate Control • ... β-Blocker • CCB • Digoxin ... Fibrillation #Cardiology #Management
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... ß blocker, or digoxin ... DrEricStrong #BRASH #Syndrome ... #diagnosis #management ... #pathophysiology
Acute Atrial Fibrillation - Initial Options for Rate Control
Diltiazem IV
 •  Rapid onset and rapidly
Initial Options for Rate ... long-term oral use Digoxin ... of action • Rate ... #Control #pharmacology ... #management #cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... : • Pathophysiology ... proliferation rate ... TLS #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Iinitial rate: 1
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess Pathophysiology ... degrees • Chills, night ... weight loss • Late ... CXR upright or lat
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Palpitations, light-headedness ... block or WPW Rate ... sinus rhythm vs rate ... atrial thrombus • Digoxin ... AFib #diagnosis #management
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Neuroleptic malignant syndrome ... tremor ("rabbit syndrome ... tremor (may be a late ... #SideEffects #pharmacology ... #management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Cytokine Activation Syndrome ... be repeated 12h later ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications