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diagnosis differential treatment oncology syndrome cirrhosis rheumatology algorithm classification encephalopathy gastroenterology hepatopulmonary leukemia monoclonal signs workup abscess adhesivecapsulitis aflp alkaline
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... #Workup #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... suspicion of severe disease ... splenomegaly, abnormal neurology ... , back pain Haematology ... - Sickle cell disease
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... Ig deposition disease ... (light chain vs ... Differential #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... proliferation rate ... TLS #diagnosis #management ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... PBC Signs and Symptoms ... • Jaundice (later ... diagnosis #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... #pathophysiology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... CKD, CHF, high rate ... Transfusion #Reactions #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Diagnosis and Management ... • Most common cause ... Lung Abscess Pathophysiology ... degrees • Chills, night ... #differential #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
present in middle to late ... childhood and late ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... : • Triad of symptoms ... of underlying disease ... #nephrology
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