35 results
diagnosis differential oncology algorithm cirrhosis monoclonal primary syndrome treatment biliary classification gammopathy pbc rheumatology workup causes cholangitis disorders hemeonc hodgkins
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... Features: POEMS, AL ... DADS-M, Sporadic, late-onset ... Ig deposition disease ... Differential #Diagnosis #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... constitutional symptoms ... myeloma and AL ... amyloidosis • Rate ... #Significance #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Diagnosis Algorithm Symptoms ... Fatigue, Pruritus, Right ... of autoimmune disease ... Elevated ALP 2. ... Diagnosis #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
RED FLAGS - In all ... suspicion of severe disease ... splenomegaly, abnormal neurology ... , back pain Haematology ... - Sickle cell disease
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... • Jaundice (later ... obstruction • ALP ... diagnosis #workup #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... hepatosplenomegaly (Rare but might ... Lymphomas • Other hematologic ... Malignancies (eg CML, ALL ... #differential #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... Ig deposition disease ... glomerulonephritis, light-chain ... Complications #diagnosis #hematology
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