14 results
diagnosis oncology differential classification disorders gammopathy mgus monoclonal significance syndrome aflp algorithm alkaline als amyotrophic apml arthritis biliary causes cholangitis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... • Jaundice (later ... obstruction • ALP ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... not required in all ... #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... Features: POEMS, AL ... DADS-M, Sporadic, late-onset ... deposition disease (light ... Differential #Diagnosis #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... TLS #diagnosis #management ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... pattern of spread, B symptoms ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... constitutional symptoms ... myeloma and AL ... amyloidosis • Rate ... #Significance #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... features developing later ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology ... #diagnosis #management
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