36 results
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics
1,3 ß-D-glucan:
 • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... Glucan-containing gauzes ... Characteristics #Sensitivity ... #Specificity #Laboratory ... #Fungi #Fungal
Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC ScoreA Systematic Review and
Necrotizing Soft Tissue Infection ... #Diagnosis #EBM ... LRINEC #Accuracy #Sensitivity ... #Specificity
Fernando SM et al. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in
With Suspected Infection ... pubmed/29404582 #EBM ... Screening #Sepsis #Sensitivity ... #Specificity #Metaanalysis
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... Galactomannan sensitivity ... associated with low sensitivity ... and low specificity ... Management #treatment #fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
dermatidis • Sensitivity ... & Specificity: ... infection (IFI) ... surfaces - Infections ... & Specificity
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... • Infectious ... : • HIV • EBV ... : • Fungal • ... Diagnosis #Algorithm #causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... 100%, specificity ... Demyelinating disease caused ... effect/Edema • EBV ... 92% and specificity
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... Bacterial • Viral (EBV ... Parasitic • Fungal ... Diagnosis #Algorithm #Causes
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... difficile (gut) • Fungi ... Toxoplasma gondii Late ... #Transplant #Infections ... differential #diagnosis #causes
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& seizures are late ... and hematologic infection ... widespread infection ... bacteremia are late ... peds #pediatrics #pathophysiology