31 results
Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC ScoreA Systematic Review and
Necrotizing Soft Tissue Infection ... #Diagnosis #EBM ... LRINEC #Accuracy #Sensitivity ... #Specificity
Fernando SM et al. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in
With Suspected Infection ... pubmed/29404582 #EBM ... Screening #Sepsis #Sensitivity ... #Specificity #Metaanalysis
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... Galactomannan sensitivity ... associated with low sensitivity ... and low specificity ... treatment #fungal #infectiousdiseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
present in 15% of cases ... 100%, specificity ... Demyelinating disease caused ... effect/Edema • EBV ... opportunistic #InfectiousDiseases
Fatality / Mortality Calculations in an Outbreak
There are a number of different types of rates, risks,
fatality rate ( ... period of time) - Infection-fatality ... with evidence of infection ... evidence of infection ... #Calculating #InfectiousDiseases
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... Toxoplasma gondii Late ... #Transplant #Infections ... differential #diagnosis #causes ... #infectiousdiseases
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& seizures are late ... and hematologic infection ... widespread infection ... bacteremia are late ... peds #pediatrics #pathophysiology
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics
1,3 ß-D-glucan:
 • Most fungi excluding mucor and
Glucan-containing gauzes ... Characteristics #Sensitivity ... #Specificity #Laboratory ... #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... +++: Virus (EBV, ... biologics (CMV +++, EBV ... Drugs, Unknown cause
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... cellars, barns and lake ... houses • Person-to-person ... chills, myalgias, nausea ... #microbiology #infectiousdiseases