9 results
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness ... of Leptospirosis ... -14 days): • Fever ... maculopapular rash ... Washington University ID
By Marcela Santana @Marcelaaos via Febrile [febrilepodcast.com @febrilepodcast]
#ID  #Infectious Diseases  #Infections
#Microbiology #Micro
#Leptospirosis #Leptospira #management
febrilepodcast] #ID ... #Infectious Diseases ... #Infections #Microbiology ... #Micro #Leptospirosis ... #Leptospira #management
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
leishmaniasis • Adult Still's ... : • Still's disease ... periodic syndrome Biphasic ... feverLeptospirosis ... • Malaria • Leptospirosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... arthritis, Skin rash ... #AdultOnset #Stills ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... maculopapular rash ... #Disease #AOSD ... rheumatology #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... with urticarial rash ... #Adult #onset #Stills ... #rheumatology #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... • Periodic fever ... - Nonremitting fever ... Petechial or purpuric rash ... Syndrome #Diagnosis #Management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... Generalized: • Chills ... night sweats, fever ... Persistent bacteremia/fevers ... Endocarditis #diagnosis #management
Summary of Monkeypox: Current Knowledge as of May 2022
 • What is Monkeypox?
 • Origins of
- Prodrome: Fever ... (>90%), chills. ... smallpox) - Rash ... Monkeypox #diagnosis #management ... infectiousdiseases #microbiology