96 results
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
: Leptospirosis, ... Rat-bite fever, ... #leptospirosis ... #management #treatment ... #table
Causes of Relative Bradycardia - Note the propensity for intracellular organisms.
Infectious: 
Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... Infectious: Legionella ... Babesiosis, Malaria, Leptospirosis ... , Non-infectious ... infectiousdiseases #table
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
INCREASES 8-10 BPM INFECTIOUS ... • Malaria • Leptospirosis ... CLINICAL UTILITY ... the most likely infection ... #differential #causes
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
and bacterial infections ... Pyogenic/focal infection ... Causes: • Still's ... • Leptospirosis ... • Malaria • Leptospirosis
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... non-productive cough, nausea ... Epidemiologic exposure + clinical ... #Leptospira #microbiology ... #diagnosis #treatment
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Drugs • ICP / Infections ... Cimetidine Infections ... Babesiosis • Leptospirosis ... Spondylarthropathies Other causes ... differential #diagnosis #causes
Travel History - Clues to Infectious Disease Diagnosis in a Traveler 
 • Where did you
Travel History - Clues ... to Infectious Disease ... rural → Geographic disease ... → Leptospirosis ... Rabies, cat scratch fever
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... Drugs, Unknown cause ... Treatment: •
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Clinical Manifestations ... 20%) congenital infection ... Mononucleosis-like disease ... virus 7 HHV-7 Fever ... #Viruses #HHV #Microbiology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #