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diagnosis differential management rheumatology renal abscess cardiology clinical endocarditis infectiousdiseases syndromes vasculitides amiodarone bronchiectasis causes chestxray classification conditions cxr dehydrogenase
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... destructive sinusitis, pulmonary ... retroorbital mass) • Microscopic ... - Interstitial lung ... and Sjogren's syndrome
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... ANCA Associated Vasculitis ... other hemorrhagic fevers ... , Leptospirosis, ... Kumfer @AnnKumfer #Pulmonary
Lung Abscess Microbiology: • Polymicrobial • Anaerobes (most common) Clinical: • Indolent symptoms that evolve
Lung Abscess Microbiology ... to rnonths • Fever ... , hemoptysis Treatment ... meropenem) #Lung ... Abscess #Diagnosis #Pulmonary
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
Leptospirosis Pathogen ... failure • Severe pulmonary ... manifestations • MAT microscopic ... #Leptospira #microbiology ... #diagnosis #treatment
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... IgA-associated vasculitis
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... disorders: - Vasculitis ... polyangiitis, microscopic ... Others: - Pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... Coronary arteries - Fever ... • Cogan Syndrome ... : • Fevers • ... Dx: GPA, EGPA, microscopic
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Interstitial lung ... Spondyloarthropathies, SLE • Pulmonary ... • Shrinking lung ... Lyme disease, Vasculitis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... palpable purpura 2/2 vasculitis ... sparing of the lung ... diagnosis #management #treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
: • 80% have fever ... Intervention: - Fevers ... hemorrhage • Treatment ... Diagnosis: • Vasculitis ... #Abscess #pulmonary
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