21 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... disease • Systemic lupus ... SJIA], systemic lupus ... #Syndrome #Diagnosis ... #Management #Hematology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... In POC redness may ... Suggestive of: Rheum Fever ... migrans: • Target sign ... gabrieltalledop #dermatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... if neutropenic fever ... Can progress to MDS ... #management #treatment ... #hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... the Nikolsky sign ... or Nikolsky sign ... may be having ... #Diagnosis #Dermatology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... red-flags to exclude dermatologic ... Ill-appearing, vital sign ... instability - New-onset fever ... #Dermatology #Rash
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... : HLH signs and ... following: • Fever ... #management #treatment ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Sweet #Syndrome #diagnosis ... #dermatology #oncology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... jaundice ​• Neuro: AMS ... coinfection, toxo reactivation ... Nodular → Mular DIAGNOSIS ... #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... dermis Clinical Signs ... inflammatory plaques (may ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... to: Arthritis, Fever ... Chronic B-cell activation ... Erythematosus #Diagnosis