12 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... if neutropenic fever ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... : HLH signs and ... following: • Fever ... #management #treatment ... #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... coinfection, toxo reactivation ... Nodular → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... Unknown cause Treatment ... #management #treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... and Management ... mild (malaise, fever ... Romana's sign ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... by uncontrolled activation ... Presentation • Common Signs ... Fever b. ... #Management #Hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... • Bilateral signs ... Mycoplasma - Leptospirosis ... Transverse Myelitis Treatment ... #management #neurology