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rheumatology disease syndrome hemophagocytic lymphohistiocytosis oncology stills adultonset aosd chronic cll hemeonc leukemia lymphocytic neurology summary symptoms activation anemia aplastic
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
also observed in adults ... : HLH signs and ... following: • Fever ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... diseases: SLE+++, Adult-onset ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Histopathologic criteria ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
to find in an adult ... - Common in: Adults ... Presentation • Common Signs ... Diagnostic Criteria ... #Management #Hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... Presentation: • Fever ... Criteria - Fever ... KD #vasculitis #rheumatology ... #management #treatment
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology # ... management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... if neutropenic fever ... #management #treatment ... #hematology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Differential Diaqnoses ... #management #treatment ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Criteria: • Elevated ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
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