63 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
IL-2 receptor Diagnostic ... Criteria for HLH ... ): Molecular diagnosis ... Lymphohistiocytosis #diagnosis ... #hematology #criteria
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Travelers from ... Frequent Differential Diagnoses ... without localizing signs ... #differential #diagnosis ... #tropical #travel
Rodent-associated Bacterial infections: Leptospirosis, Rat-bite fever, Tularemia, Plague 

#rodent
#infections
#leptospirosis
#tularemia
#ratbitefever
#plague
#rats
#infectiousdisease
#fever
#differential
#diagnosis
#management
#treatment
#table
, Rat-bite fever ... infectiousdisease #fever ... differential #diagnosis ... #management # ... treatment #table
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Presentation / Diagnosis ... : HLH signs and ... Diagnosis via genetic ... Infection should be diagnosed ... #management #treatment
Criteria for Patients Under Investigation for 2019 Novel Coronavirus (2019-nCoV) / COVID-19

Fever or signs/symptoms of lower
Criteria for Patients ... AND A history of travel ... AND A history of travel ... nCoV2019 #COVID19 #Criteria ... #Diagnosis #Wuhan
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... hemophagocytosis = additional diagnostic ... Lymphohistiocytosis #diagnosis ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Histopathologic criteria ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... Aplastic #Anemia #diagnosis ... #management #treatment ... #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... infections Diagnostic ... Criteria - Fever ... #pediatrics #diagnossi ... #management #treatment