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rheumatology differential management classification arthritis erythematosus hemophagocytic hlh joint lupus lymphohistiocytosis msk oncology syndrome systemic vasculitis approach bowel chronic cll
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... thin smear • Signs ... Clinical findings of PAN ... values supporting hematologic ... #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Travelers from ... Frequent Differential Diagnoses ... without localizing signs ... • Abdominal pain ... #differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... erythematosus [SLE ... Histopathologic criteria ... #Syndrome #Diagnosis ... #Management #Hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
and Workup Summary ... Rome IV Criteria ... Recurrent abdominal pain ... missing things" → fewer ... #workup #gastroenterology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... : HLH signs and ... following: • Fever ... agent are the main ... management #treatment #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... • Rheumatic fever ... arthritis • SLE ... #MSK #rheumatology
Modified dengue severity classification, PAHO/WHO Dengue without warning signs - DNWS: • Person who lives or has
who lives or has traveled ... days and presents fever ... the following criteria ... retro-orbital pain ... classification #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... Arthritis: • Joint pain ... to: Arthritis, Fever ... Chronic B-cell activation
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... acute rheumatic fever ... Chronic = RA, SLE ... approach #workup
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