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Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Travel History - Clues to Infectious Disease Diagnosis in a Traveler • Where did you
Disease Diagnosis ... rural → Geographic disease ... → Leptospirosis ... Rabies, cat scratch fever ... #differential #Diagnosis
Fever in Returning Traveler - ABCDE Mnemonic A - Adventure - Where did the patient travel? B
Fever in Returning ... exposures to onset of symptoms ... Ill Contacts Infectious ... Diseases Fellows ... Mnemonic #history #diagnosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Workup • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Leptospirosis ... Brucellosis Faget's Sign ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
brief interval symptom ... -14 days): • Fever ... dysfunction) • Pulmonary ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... other hemorrhagic fevers ... , Leptospirosis, ... #Differential #Diagnosis
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
Etiologies Unusual Infections ... psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... ) - Returning travelers ... NonResolving #Pneumonia #diagnosis
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Clinical: • Disease ... Constitutional: Fever ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs ... #Pulmonary
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
Travel Infectious ... : • Leptospirosis ... cases of malaria diagnosed ... and myalgias, symptoms ... culture; rapid diagnostic
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