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differential rheumatology oncology vasculitis biphasic chronic classification cll disorders emergencies eosinophil eosinophilia fuo hemeonc illness leukemia lymphocytic oncologic phases returning
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... ’ algorithm • ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
brief interval symptom ... -14 days): • Fever ... dysfunction) • Pulmonary ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... #diagnosis #signs ... #symptoms #testing ... #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... #workup #oncology ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... Presentation - Systemic Symptoms ... Vasculitis: • Fevers ... purpura: strong sign ... #rheumatology #
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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