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differential rheumatology lupus sle systemic infections infectiousdiseases management symptoms vasculitis workup activation aids autoantibodies chronic classification cll dermatology erythematous febrile
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
- THE ALGORITHMIC ... staphylococcal scalded skin syndrome ... and toxic shock syndrome ... #Diagnosis #Dermatology ... Rash #Algorithm
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... ’ algorithm • ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #signs #symptoms ... #diagnosis #rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Leptospirosis ... Brucellosis Faget's Sign ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... - Hemolytic anemia ... #signs #symptoms ... #differential #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... systemic lupus erythematosus ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever ... #Diagnosis #Rheumatology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
region Viral Syndromes ... ; dengue shock syndrome ... capillary leak syndrome ... Infections: • Leptospirosis ... No hemolytic anemia
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential Diagnosis ... Pneumonia: • 3 syndromes ... • CT: Halo sign ... papules, pustules, erythematous ... 100% of cases), anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... • Neutropenia, anemia ... • Richter’s Syndrome ... workup #oncology #hematology
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