11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... of Pregnancy (AFLP ... ) Three syndromes ... #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Identify Acute Liver ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Biliary Cirrhosis - Diagnosis ... quadrant discomfort Signs ... Elevated ALP 2. ... Liver biopsy findings ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #differential #diagnosis ... #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... and hepatorenal syndrome ... • Budd Chiari syndrome ... sarcoidosis) • Liver ... #causes #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... Areas of diagnostic ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... failure PBC Signs ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Diagnosis via genetic ... lymph node, or liver ... management #treatment #hematology