13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... Differential Diaqnoses ... Complications: MAS ... management #treatment #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... weeks - Typical skin ... #AdultOnset #Stills ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... Still disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... mL Gf consider MAS ... #onset #Stills ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... rheumatoid arthritis, adult-onset ... Still disease, ... #Rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... years - Rare in adults ... pressure areas (may ... HenochSchonleinPurpura #HSP #Diagnosis ... #Rheumatology #
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Insect stings Disease ... Disorientation, vertigo Diagnostic ... histology - Mast ... Cold #Urticaria #diagnosis ... #rheumatology #
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... be seen in travelers ... Adult hookworms ... self-limited Diagnosis ... #clinical #photo
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... arthritis • Adult ... onset Still's ... #Differential #Diagnosis ... #MSK #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... myopathy • Anti MAG ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis