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management differential algorithm dermatology rheumatology syndrome hepatology generalized lymphadenopathy pruritus secondary systemic thrombocytosis classification cll diffuse druginduced hemeonc lad lupus
Chronic Myelomonocytic Leukemia (CMML) • Definition • DDx • Dx Tool and Risk Stratification • Treatment
Chronic Myelomonocytic ... Leukemia (CMML) ... Stratification • Treatment ... #CMML #oncology ... #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Myelogenous Leukemia ... : • Acute or Chronic ... effect following treatment
Chronic Neutrophilic Leukemia (CNL) • Signaling Pathway • WHO Dx Critera • Risk Stratification • Treatment
Chronic Neutrophilic ... Leukemia (CNL) ... Stratification • Treatment ... #Neutrophilic #Leukemia ... #diagnosis #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Age > 50 • Chronic ... #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... - Differential Diagnosis ... • Neoplastic (Leukemia ... #Algorithm #Causes ... #Hematology #Oncology
Differential Diagnosis for Generalized Lymphadenopathy Viral • HIV • EBV • CMV • HBV • Dengue • Rubella
Differential Diagnosis ... Syphilis • Lyme • Leptospirosis ... • Lymphoma • Leukemia ... #Causes #Algorithm ... #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute leukemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... - Differential Diagnosis ... Myeloproliferative Disorder • Chronic ... #Algorithm #Causes ... #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
- Differential Diagnosis ... Myelofibrosis • Chronic ... Myeloid Leukemia ... #causes #Platelets ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... hemorrhage) • Chronic ... myeloid leukemia ... #Causes #hematology
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