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differential management oncology causes clinical photo skinrash algorithm leukemia eosinophilia hemeonc lymphocytic rash rheumatology syndrome antinxp2 antinxp2dm atopic atopy basophilia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... (Chronic Myeloid ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... Diagnosis: • ... microglobulin Treatment ... workup #oncology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... • Infections: Chronic ... post-splenectomy, Exercise, Allergic ... #Algorithm #hematology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Blastomycosis Skin ... Denies any travel ... Diagnosis? ... ca, squamous cell ... Blastomycosis #SkinRash #dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
causes are asthma, allergy ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential Diagnosis ... Rhinitis - Allergic ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic ... #Causes #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... released during an allergic ... Disorders: • Chronic ... #Differential #Diagnosis ... #causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... minimal tumor burden Diagnosis ... #Chronic #Lymphocytic ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... - Differential Diagnosis ... lichenification (chronic ... anyone - Allergic ... Eczematous #SkinRash #dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... , breast CA - Hematologic ... CANDLE syndrome - Allergic ... Treatment: - Systemic ... #dermatology #oncology
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