24 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... , PRES Pathophysiology ... #neurology #rheumatology ... cerebritis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Facial nerve (7th CN ... Burgdorferi (Lymes disease ... #Bells #Palsy #neurology ... #anatomy #pathophysiology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Scleromyxedema (CNS ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
(idiopathic), CNS ... floor muscle and ligament ... Incontinence #Mixed #Pathophysiology ... Signs #Symptoms #Urology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... nervous system (CNS ... of underlying disease ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... causes #treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
PUNISH Mnemonic - Indications for Head CT before Lumbar Puncture (LP)

P - Papilledema
U - Unconsciousness
N -
Unconsciousness N - Neurologic ... H - History of CNS ... disease (mass, ... #Puncture #LP #Neurology ... #Management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
for worsening disease ... therapy (MMF plus CNI ... Algorithm #Treatment #management ... #nephrology