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diagnosis signs syndrome differential treatment alkaline alp apml arteritis behcet causes cerebritis coagulation crisis dic differentiation disease disseminated erythematosus fungal
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... symptoms (headache ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
(idiopathic), CNS ... floor muscle and ligament ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... causes #treatment #management ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... them, but urgent rheumatology ... absence of visual symptoms ... Temporal #Signs #Symptoms ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
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