23 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
100% Hepatic, 0% Renal ... 75% Hepatic, 25% Renal ... 20% Hepatic, 80% Renal ... NOAC #Metabolism #Pharmacology ... Clearance #oral #anticoagulation
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduction #Dose #Anticoagulation ... #Pharmacology # ... AFib #Renal #CKD
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Monitoring - Renal ... Resume #Oral #Anticoagulation ... Management #Table #Pharmacology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
1 A Abnormal renal ... liver function Renal ... (renal replacement ... CHADS2VASc #HASBLED #Comparison ... AFib #Diagnosis #Hematology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Rivaroxaban • Renal ... Bloodman #DOAC #anticoagulation ... #dosing #ckd #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Prophylaxis, VTE and Renal ... Dosing Renal ... Apixaban (25% renal ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
Cardiovascular and renal ... effects comparison ... cardiovascular #renal ... SGLT2i #Inhibitors #pharmacology
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
clearance - Anticoagulation ... monitored - Ok in renal ... contraindicated in renal ... LMWH #Heparin #comparison ... Unfractionated #pharmacology
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose Comparison ... potassium, and renal ... Dosing #Conversion #Pharmacology ... #PrimaryCare #Comparison
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
coagulopathy - LMWH • Renal ... decisionaid #vte #anticoagulation ... #pharmacology