23 results
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
Cardiovascular and renal ... effects comparison ... cardiovascular #renal ... SGLT2i #Inhibitors #pharmacology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
into the deeper retinal ... macula, and/or retina ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose Comparison ... potassium, and renal ... Dosing #Conversion #Pharmacology ... #PrimaryCare #Comparison
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Renal Effect of ... Synthesis - Renal ... disease -> Decreased renal ... Prostaglandins #Pharmacology ... #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium #Renal
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Signs / Symptoms / Complications ... absent or partial retinal ... spread • Sub-retinal ... Retinoblastoma #pathophysiology ... #ophthalmology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment of renal ... #Pharmacology #Pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
nervefiber layer -> Retinal ... of the terminal retinal ... #Retinopathy #pathophysiology ... #ophthalmology ... signs #symptoms #complications
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
monitored - Ok in renal ... contraindicated in renal ... LMWH #Heparin #comparison ... Unfractionated #pharmacology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
filtration - Renal ... stretch - decreased renal ... blood flow and renal ... Instability: - Renal ... #pharmacology #