10 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... Massive proteinuria ... Classification #Proteinuria ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... (Positive urine ... albuminuria) - Active urine ... #Nephrology #Differential
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Hyperoxalirua, Heavy Proteinuria ... , Lipiduria, Tuberculosis ... (blue diaper syndrome ... Bag Syndrome - ... Differential #Diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... high-power field + acanthocytes ... #nephrotic #syndrome ... #nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Urine Specific Gravity ... Gravity = Density of urine ... Dehydration • SIADH (syndrome ... Glycosuria • Proteinuria ... #differential #nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range proteinuria ... : - Urine total ... defined as nephrotic syndrome ... classification #CKD #nephrology ... #diagnosis #proteinuria
Hepatorenal Syndrome Diagnosis
 • ↑ in serum Cr of ≥ 0.3mg/dL above baseline
Hepatorenal Syndrome ... (including no proteinuria ... ) • ↓ urine output ... 2 HRS) • Low urine ... diagnosis #HRS #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... pain hematuria syndrome ... - Proteinuria ... • Nutcracker syndrome ... causes #urology #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... anti-phospholipid syndrome ... Glomerulonephritis #MPGN #nephrology