10 results
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
examination, check urine ... uric acid: - Urine ... sodium low, uric ... - Urine sodium ... Algorithm #Diagnosis #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Osmolarity 2) Urine ... Osmolarity 3) Urine ... Uric Acid - Low ... Diagnosis #Algorithm #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
uric acid >4 • Urine ... Extra-renal losses • Urine ... uric acid >4 • Urine ... Nephrotic syndrome • Urine ... #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... 145 mmol/L High Urine ... mannitol, glucosuria Low ... Urine Osmolality ... #Nephrology #Differential
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... → Increased urine ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... Algorithm 1) Check Urine ... Extrarenal Hypernatremia ... • Euvolemic (Low ... Workup #Algorithm #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... volume-based algorithm Urine ... can be high or low ... Primary polydipsia), Low ... table #sodium #nephrology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
renal function/urine ... produces them when low ... precipitant. 5) treat low ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
is decreased), hypernatremia ... ↑ 24-hour urine ... levels following a low-dose ... signs #symptoms #endocrinology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
alkalosis • Normal or low ... Hypocalciuria (spot urine ... Syndrome #diagnosis #nephrology ... #management #pathophysiology