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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... RBCs in urine)?
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... hematuria. ... RBC casts in urine ... but in severe cases
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
: Red/Dark urine ... 1ml blood/liter urine ... more RBC/HPF spun urine ... examination of urine ... : - RBC casts
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal Urine ... * Green Urine: ... Bag Syndrome - ... : • Hematuria, ... : • Hematuria,
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Symptoms of UTI, urine ... WBCs, or urine ... → Urine culture ... proteinuria, RBC casts ... urology #blood #urine
Abnormally Colored Urine - Differential Diagnosis Framework
Red:
 - Hematuria, Hemoglobinuria, Myoglobinuria
 - Beets, Rhubarb, Blackberries, Artificial
Abnormally Colored Urine ... Framework Red: - Hematuria ... Purple: - Purple urine ... bag syndrome (chronically ... AnnKumfer #Colored #Urine
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... Casts • Hyaline ... suggestive of nephrotic sydnrome ... #Urine #Microscopy
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Hematuria in Post-Renal ... (Goodpasture's syndrome ... TheIDtrivia #Hematuria ... kidney #blood #urine ... #management #treatment
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Urinalysis & Urine ... exclusively on urine ... • Urinary casts ... #UNa #casts #glucosuria ... #hematuria
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... RBCs and/or RBC casts ... ) - Isolated Hematuria ... ) - Isolated Hematuria