13 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Clinical Features ... Induced Lupus: • Symptoms
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... dermatomyositis, SLE ... #differential # ... dermatology #oncology #clinical ... #skin
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... systemic lupus erythematosus ... (SLE) Signs / ... Symptoms: - Lymphocyte ... Xeroderma (Dry skin
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Demyelinating syndromes ... #systemic #erythematosus ... #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Systemic Lupus Erythematosus ... (SLE), should have ... other symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... (Clinical Dx). ... Behcet disease) Differential ... Oral aphthae : SLE ... • Arthritis: SLE
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Syndrome (SS), ... Arthritis, Sjögren Syndrome ... rheumatology #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... aphthous ulcers, cutaneous ... Presentation - Systemic Symptoms ... strong sign of cutaneous ... vasculitis, and SLE
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... : • Clinical triad ... reticularis & skin ... Henoch-Schönlein purpura) • Cutaneous ... systemic lupus erythematosus
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... weakness without skin ... systemic lupus erythematosus ... (SLE), polymyositis ... IU/I • SAMS clinical