25 results
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
: 2-8 weeks • Rash ... with erosions • CBC ... Tubulointerstitial nephritis • Skin ... : 4-28 days • Rash ... Prerenal azotemia • Skin
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... ulcerations • Skin ... ulcerations • Auricular skin ... 50% of cases • Skin
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
stage into the skin ... pathophysiology #infectiousdiseases ... #cdc #parasite
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... sudden onset of a rash ... - Rash: multiple ... - CBC may also
Clonorchiasis - Clonorchis sinensis Life Cycle
1) Embryonated eggs passed in feces.
2) Eggs ingested by the snail
encyst in the skin ... Metacercariae in flesh or skin ... pathophysiology #infectiousdiseases ... #cdc #parasite
Intestinal Hookworm Life Cycle
1) Eggs in feces
2) Rhabditiform larva hatches
3) Development to filariform larva in environment
4)
larva penetrates skin ... pathophysiology #infectiousdiseases ... #cdc #parasite
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... regeneration, diffuse CD8
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
penetrate the intact skin ... pathophysiology #infectiousdiseases ... #cdc
Onchocerciasis - Onchocerca volvulus Life Cycle
1) Blackfly (genus Simulium) takes a blood meal (L3 larvae enter
typically are found in skin ... pathophysiology #infectiousdiseases ... #cdc #parasite
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... mucositis - Rash ... Small Vessels: Skin ... Lab Tests: • CBC