25 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar rash ... life-threatening • Treatment ... lupus #Systemic #Erythematosus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... severe disease Treatment ... Systemic #Lupus #Erythematosus ... #rheumatology #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... 3rd Decade Skin ... rash • Erythematous ... Seizures • Strokes Skin ... Induced Lupus: • Symptoms
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... • Treatment: ... Systemic Lupus Erythematosus
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #systemic #erythematosus ... #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
arthritis - with the skin ... Systemic Lupus Erythematosus ... (SLE), should have ... other symptoms ... like “butterfly rash
Lyme Disease: Clinical diagnosis. Likely if recent hiking, travel to endemic area, erythema migrans (EM), an
migrans (EM), an erythematous ... Treatment is doxycycline ... disease involving skin ... carditis, meningitis (see ... #LymeDisease #Symptoms
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... with or without treatment ... , but without treatment ... Diagnosis #Clinical #Photo
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... systemic lupus erythematosus ... (SLE), polymyositis ... myopathy #diagnosis #management ... #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic Symptoms ... rash in association ... Symptoms: • The ... Skin involvement ... disease: symptomatic treatment