80 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... thickening Signs ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Heliotrope sign ... or shawl sign ... Interstitial lung disease ... tract - Cardiac disease ... Dermatomyositis #Diagnosis #Rheumatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... disease, Pulmonary ... disease (~93-95% ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... infection • Lyme disease ... migrans • Lyme disease ... Sarcoidosis • Crohn's disease ... differential #diagnosis #rheumatology
Breast Cancer - Visible Signs on Physical Examination:

Retraction, Abnormal Contours, Skin Dimpling, Nipple Retraction, Edema, Paget's
Cancer - Visible Signs ... Abnormal Contours, Skin ... Edema, Paget's Disease ... BreastCancer #Visible #Signs
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... cancers • Systemic diseases ... autoinflammatory diseases ... management #treatment #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... diagnosis #management #signs ... #symptoms #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... GPA causes disease ... vasculitis Skin ... also occur Skin ... rash #diagnosis #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
the population Disease ... trigger - Direct skin ... 50% of patients Skin ... 1% of patients Skin ... Urticaria #diagnosis #rheumatology
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... common primary disease ... Manifestations #Disease ... Systems #Diagnosis #Hematology ... #Signs #Symptoms