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causes disease hematology spinal spinalcord agglutinin algorithm behcet caudaequina disorders equina generalized hemolytic lesions management monoclonal oncology paraproteinemias rheumatology signs
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... - Mycoplasma, EBV ... younger pts) Differential
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... result in permanent neurologic ... involvement Cauda ... #differential # ... diagnosis #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... lumbar spine • MCC ... Spinal cord infarct ... spondylitis • Tethered cord ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Spinal cord ... neurological lesion: Clinical ... Lower roots -> Cauda ... #neurology #differential
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Diagnosis Framework ... Infectious: Influenza, EBV ... : CHF, valves, COPD ... ILD, OSA, pHTN, Anemia ... #neurology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... due to cold IgG ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... matter, spinal cord ... (Clinical Dx). ... Behcet disease) Differential
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