16 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
common in SLE, autoimmune ... biliary cirrhosis (PBC ... Anti-GBM - Goodpasture's ... #diagnosis #table ... #rheumatology #
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... obstruction, HELLP Syndrome
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Membrane): - Autoimmune ... Drug-associated, PCH ... , Evans Syndrome ... #Diagnosis #hematology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
- Compatible syndrome ... toxo IgG • CNS PCR ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... HBV, HCV, HEV, EBV ... • Autoimmune:
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... pts) Differential
Rhombencephalitis
BACTERIAL
- Listeria (biphasic illness with bulbar dysfunction occurring later)
- Mycobacterium tuberculosis
- Pneumococcus
- Brucella
- Borrelia (Lyme Disease)
-
Viruses (HSV, EBV ... Toxoplasmosis AUTOIMMUNE ... Rhombencephalitis #Differential ... #Diagnosis #Causes ... #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... - SLE Neurologic ... ear, sparing the lobe ... #joint #pain #differential ... #diagnosis #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
occipital and parietal lobes ... /Sepsis/Shock, Autoimmune ... disease, Cancer ... Reversible course Differential ... #neurology