375 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Osmotic agents (mannitol ... urearetics) 3) Loop
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Diuretics (e.g. mannitol ... ) 3) Loop Diuretics
Overview of effects of diuretics and hormones involved in fluid homeostasis.

#diruetic #diuretics 
#aldosterone #ADH #ANP #BNP
#thiazide
hydrocholorothyazide #loop ... diamox #osmotic #mannitol
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
diuretics (e.g. mannitol ... ) 3) Loop diuretic
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
empagliflozin LOOP ... DIURETICS • Mannitol
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
POCUS Amazing video ... significantly, it causes ... echogenic as in this case ... Always look for ... underlying cause
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Furosemide and other loop ... Thiazides - Mannitol ... diagnosis #nephrology #Causes
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
Resolution of AKI • Mannitol ... Differential #Diagnosis #Causes
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... ), Isosorbide, Mannitol ... nephrology #conversion #loop ... #thiazide #classes
Approach to determining the cause of a blood clot
1) Is it acquired?
2) Should you consider inheritable
determining the cause ... consider inheritable causes ... 3) Should you look ... VTE #diagnosis #causes